Prepare slaughter for his children,.... These words are directed to the Medes and Persians, to prepare instruments of slaughter, and make use of them; and prepare themselves for the slaughter of the whole royal family, Belshazzar and all his children.
So it is threatened to Jezebel, or the Romish antichrist, that all her children should be killed with death, Re 2:23:for the iniquity of their fathers; they imitating and following them in their sins, partaking of them, and filling up the measure of their iniquities:that they do not rise, nor possess the land; stand up and succeed him in the government of the land, as their inheritance:nor fill the face of the world with cities; as their ancestors had done, which were built by them to perpetuate their name and glory, and to keep the nations in awe subdued by them.