This is by some supposed to be some bodily disease inflicted on him; some have thought of the leprosy, which was a stroke from the hand of God; but this is not likely, since he must have been deposed and shut up; the Jews indeed say that he was a leper six months, and that the divine Presence was taken from him; a late learned man thinks it was the smallpox, from the unsoundness of his flesh, the soreness of the disease, the stench of it, temporary blindness, and his friends standing aloof from him; though perhaps no other than affliction of mired for sin, comparable to the disease described, is meant.
In R. Obadiah in loc. De Laney's Life of King David, vol. 2. p.