It shall never be inhabited. This part of the prophecy did not receive its fulfillment till many centuries had gone by. From the time of Cyrus to that of Alexander the Great, Babylon was one of the chief cities of the Persian empire.
Alexander was so struck with it, and with the excellence of its situation, that he designed to make it his capital. It first began seriously to decline under the Seleucidae, who built Seleucia on the Tigris as a rival to it, and still further injured it by fixing the seat of government at Antioch.
But it had still a large population in the first century after our era (Josephus, 'Ant. Jud.,' 18.9, § 8); and is mentioned as a place of some consequence in the time of Trajan (Die Cass; 68.27), and even in that of Severue (Die Cass; 75.
9). But after this it went rapidly to decay. Under the Sassuntans it disappears from sight; and when Benjamin of Tudela, in the twelfth century, visited the spot, there was nothing to be seen of the mighty city but those ruins of the Kasr, or palace, which still arrest the traveler's attention.
The site had become, and has ever since remained, "without inhabitant." Neither shall the Arabian pitch tent there. A superstitious feeling prevents the Arabs from encamping on the mounds of Babylon, which are believed to be the haunts of evil spirits.
Neither shall the shepherds make their fold there. The nitrous soil of the Babylonian mounds allows them to produce nothing but the coarsest and most unpalatable vegetation. The shepherds consequently do not feed their flocks on them.