And God Almighty bless thee,.... This is not a new blessing, distinct from that in Ge 28:1, but the same; there it is expressed in general, here the particulars of it are given; and by which it appears, that Isaac's blessing Jacob was a prayer, wishing a blessing from God upon him, and was the prayer of faith, delivered out under the spirit of prophecy; and they are blessed indeed that are blessed of God, and they must needs be blessed who are blessed by the Almighty; for what is it he cannot do or give?
The Targum of Jonathan adds,"with much riches;''but no doubt all kind of blessings are included, both temporal and spiritual:and make thee fruitful, and multiply thee; with a numerous offspring:that thou mayest be a multitude of people; or an "assembly" or "congregation" of them; which may all unite in one body and make one nation, as the twelve tribes descending from Jacob did.