I cry unto thee, and thou dost not hear me. It is the worst of all calamities to be God-forsaken, as Job believed himself to be, because he had no immediate answer to his prayers. The bitterest cry upon the cross was "Eli, Eli, lama sabachthani?"
But no good man is ever really God-forsaken, and no rightful and earnest prayers are ever really unheard. Job "had need of patience" (Hebrews 10:36), patient as he was (James 5:11). He should have trusted God more, and complained less.
I stand up, and thou regardest me not; rather, I stand up, as the manner of the Jews usually was in prayer (Luke 18:11), and thou lookest at me (see the Revised Version). Job's complaint is that, when he stands up and stretches out his hands to God in prayer, God simply looks on, does nothing, gives him no help.