If he will contend with him; rather, if he should desire to contend with him; i.e. if, notwithstanding his knowledge of his own weakness and guilt, he should nevertheless be mad enough to desire to contend with God, then he will find that he cannot answer him one of a thousand.
Of the charges which God might in his omniscience bring against him, he could not make a satisfactory reply to one in a thousand. It is not that Job admits any special guilt in himself; but such he feels to be the universal condition of humanity.
"All have sinned in ten thousand ways, "and come short of the glory of God" (Romans 3:23).