Set your affections on things above,.... For unless the affections are set on them, they will never be sought after in a proper manner. The word signifies to mind them, and think on them, to favour and approve of them, to be affectionately desirous of them, and concerned for them; for where the treasure is, the heart should be; and as the saints' best things are above, their minds and affections should be there likewise; their contemplation should be on those things, and their conversation should be in heaven; nor should they regard anything but what is there, or comes from thence, for they belong not to this world, but to another and better country: their citizenship is in heaven, and there, in a short time, they must have their everlasting residence; and therefore should seek after, and highly prize and value heavenly things, and set their affections on them, andnot on things on the earth; not mind earth and earthly things, temporal enjoyments, riches, and honours; and though food and raiment, and the necessaries of life, are to be sought after, and cared and provided for, yet not with anxiety and perplexity of mind, in an over thoughtful and distressing manner; nor should the heart be set on those outward things, or happiness placed in the possession of them.
Moreover, worldly lusts, the members which are on the earth, earthly pleasures that are sinful, may be here meant.