I am the vine, ye are the branches,.... Christ here repeats what he said of himself, "the vine", for the sake of the application of "the branches" to his disciples: which expresses their sameness of nature with Christ; their strict and close union to him; and the communication of life and grace, holiness and fruitfulness, of support and strength, and of perseverance in grace and holiness to the end from him:he that abideth in me, and I in him; which is the case of all that are once in Christ, and he in them:the same bringeth forth much fruit; in the exercise of grace, and performance of good works; and continues to do so as long as he lives, not by virtue of his own free will, power, and strength, but by grace continually received from Christ:for without me ye can do nothing; nothing that is spiritually good; no, not anything at all, be it little or great, easy or difficult to be performed; cannot think a good thought, speak a good word, or do a good action; can neither begin one, nor, when it is begun, perfect it.
Nothing is to be done "without Christ"; without his Spirit, grace, strength, and presence; or as "separate from" him.