Son of man, set thy force toward the south,.... The land of Judea, which lay south of Babylon, where the prophet now was, as Babylon lay north of that, Jer 1:14 to set his face was to speak freely and boldly, with courage and constancy, and without fear and dread, to the inhabitants of it; and as a token of the Lord's face being set against them for their sins.
The Targum is,"take a prophecy towards the way of the south.'