And I will set my face against that man,.... And look him out of countenance, notwithstanding all his daring impudence and presumption in coming to a prophet of the Lord, and inquiring of him by him, when guilty of gross idolatry; which mast needs be the case, when the face of God is set against a man.
The Targum renders it, "my fury", or "wrath"; and indeed that is what is meant; when God sets his face against a man, he pours out his wrath, or inflicts punishment on him; see Ps 34:16. Jarchi's note is,"as a man that says I am at leisure from all business, and I will attend to this;''laying aside all other business, wholly giving himself up to one thing, on which he is set.
Dreadful is a man's case, when the Lord thus sets himself against him!