Slay utterly old [and] young, both maids, and little children,and women,.... All, of them objects of compassion, because of their age and sex; and yet none to be spared; and which orders were exactly obeyed; see 2Ch 36:17;but come not near any man on whom [is] the mark; these were not to be slain; and though some were carried captive, as Daniel, and others; yet it was for their good and God's glory; see Re 7:3;and begin at my sanctuary; the temple, the house of God, and the priests and Levites that dwelt there.
The Septuagint version is, "begin at my saints"; those who professed themselves to be the saints of the Lord, and were separated and devoted to his service; and so the Rabbins say , do not read yvdqmm, "at my sanctuary"; but yvdwqmm, "at those that sanctify me", or "my sanctified ones"; which they interpret of those that keep the whole law, from "aleph" to "tau"; see 1Pe 4:17;then they began at the ancient men which [were] before the house; the seventy elders of Israel, who offered incense to the idols portrayed upon the walls of the chambers of the temple, Eze 8:10; these they slew first.
T. Bab. Avoda Zara, fol. 4.