Damascus is waxed feeble,.... Or, "is become remiss" ; her hands hang down, not being able through fear and fright to lift them up against the enemy; that is, the inhabitants of Damascus, as the Targum:[and] turneth herself to flee; instead of going out to meet the enemy, the inhabitants of this city meditated a flight, and turned their backs upon him in order to flee from him, and escape falling into his hands:and fear hath seized on [her]: or, "she seized on fear" ; instead of seizing on arms, and laying hold on them to defend herself with, she seized on that; or however that seized on her, and made her quite unfit to stand up in her own defence:anguish and sorrows have taken her as a woman in travail;See Gill on "Jer 49:22"; A phrase often used to express the sudden and inevitable destruction of a people, and their distress and inability to help themselves.
htpr "remissa erit", Junius & Tremellius; "remissa est", Cocceius, Piscator; "remissa facta est", Schmidt.